abstract：OBJECTIVE:To evaluate the spectrum and antibiotic susceptibility panel of infectious keratitis at a major tertiary care referral eye center and a major county hospital in Southern California. DESIGN:Retrospective case series. PARTICIPANTS:All cultured infectious keratitis cases from July 1, 2008, through December 31,...

journal_title：Ophthalmology

authors： Sand D,She R,Shulman IA,Chen DS,Schur M,Hsu HY

更新日期：2015-05-01 00:00:00

abstract：OBJECTIVE:To evaluate the clinical outcome of mid-stromal isolated Bowman layer transplantation, a new surgical technique to reduce and stabilize ectasia in eyes with advanced keratoconus, to postpone penetrating keratoplasty or deep anterior lamellar keratoplasty, and to enable continued daily contact lens wear. DESI...

journal_title：Ophthalmology

authors： van Dijk K,Liarakos VS,Parker J,Ham L,Lie JT,Groeneveld-van Beek EA,Melles GR

更新日期：2015-05-01 00:00:00

abstract：OBJECTIVE:To determine whether lamina cribrosa (LC) depth (LCD) and LC thickness (LCT) are associated with a faster rate of progressive retinal nerve fiber layer (RNFL) thinning in primary open-angle glaucoma (POAG). DESIGN:Prospective, observational study. PARTICIPANTS:One hundred ten eyes diagnosed with POAG (n = 1...

journal_title：Ophthalmology

authors： Lee EJ,Kim TW,Kim M,Kim H

更新日期：2015-04-01 00:00:00

abstract：PURPOSE:To evaluate the growth of geographic atrophy (GA) during anti-vascular endothelial growth factor (VEGF) therapy. DESIGN:Cohort within a clinical trial. PARTICIPANTS:Patients included in the Comparison of Age-related Macular Degeneration Treatments Trials (CATT). METHODS:Participants were randomly assigned to...

journal_title：Ophthalmology

authors： Grunwald JE,Pistilli M,Ying GS,Maguire MG,Daniel E,Martin DF,Comparison of Age-related Macular Degeneration Treatments Trials Research Group.

更新日期：2015-04-01 00:00:00

abstract：PURPOSE:To investigate the associations of IL17A, IL17F, IL23A, and IL23R copy number variants (CNVs) with Vogt-Koyanagi-Harada (VKH) syndrome and Behçet's disease (BD) and the possible mechanisms involved. DESIGN:Two-stage case-control and functional studies. PARTICIPANTS:A total of 1159 VKH patients, 1036 BD patien...

journal_title：Ophthalmology

authors： Hou S,Liao D,Zhang J,Fang J,Chen L,Qi J,Zhang Q,Liu Y,Bai L,Zhou Y,Kijlstra A,Yang P

更新日期：2015-03-01 00:00:00

abstract：PURPOSE:To evaluate the association between cystoid macular edema (CME) observed in very preterm infants and developmental outcomes at 18 to 24 months corrected age. DESIGN:Cohort study. PARTICIPANTS:Infants born at or less than 1500 g or at or less than 30 weeks postmenstrual age who underwent screening for retinopa...

journal_title：Ophthalmology

authors： Rothman AL,Tran-Viet D,Gustafson KE,Goldstein RF,Maguire MG,Tai V,Sarin N,Tong AY,Huang J,Kupper L,Cotten CM,Freedman SF,Toth CA

更新日期：2015-03-01 00:00:00

abstract：PURPOSE:To describe a newly recognized clinical syndrome consisting of ptosis, diplopia, vertical gaze limitation, and abduction weakness that can occur after orbital roof removal during orbito-zygomatic-pterional craniotomy. DESIGN:Case series. PARTICIPANTS:Eight study patients (7 women), 44 to 80 years of age, with...

journal_title：Ophthalmology

authors： Desai SJ,Lawton MT,McDermott MW,Horton JC

更新日期：2015-03-01 00:00:00

abstract：OBJECTIVE:To examine the impact of glaucoma and visual acuity (VA) and visual field (VF) losses on psychosocial functioning (PF). DESIGN:Cross-sectional study. PARTICIPANTS:We compared PF between 192 participants with bilateral glaucoma with VA or VF losses and 40 controls from a tertiary eye hospital clinic in Singa...

journal_title：Ophthalmology

authors： Chan EW,Chiang PP,Liao J,Rees G,Wong TY,Lam JS,Aung T,Lamoureux E

更新日期：2015-03-01 00:00:00

abstract：OBJECTIVE:To evaluate whether an ophthalmologist-led, non-anesthesia-supported, limited monitoring pathway for phacoemulsification/intraocular lens cataract surgery, can be performed safely with only a medical emergency team providing support. DESIGN:Retrospective, observational, cohort study. PARTICIPANTS:All patien...

journal_title：Ophthalmology

authors： Koolwijk J,Fick M,Selles C,Turgut G,Noordergraaf JI,Tukkers FS,Noordergraaf GJ

更新日期：2015-02-01 00:00:00

abstract：OBJECTIVE:To compare baseline characteristics, treatment frequency, visual acuity (VA), and morphologic outcomes of eyes with >50% of the lesion composed of blood (B50 group) versus all other eyes (Other group) enrolled in the Comparison of Age-Related Macular Degeneration Treatments Trials (CATT). DESIGN:Prospective ...

journal_title：Ophthalmology

authors： Altaweel MM,Daniel E,Martin DF,Mittra RA,Grunwald JE,Lai MM,Melamud A,Morse LS,Huang J,Ferris FL 3rd,Fine SL,Maguire MG,Comparison of Age-related Macular Degeneration Treatments Trials (CATT) Research Group.,Comparison of Age-r

更新日期：2015-02-01 00:00:00

abstract：OBJECTIVE:To study the anatomic and visual outcomes of a surgical procedure in which tissue plasminogen activator and air are injected subretinally to displace massive submacular hemorrhages secondary to age-related macular degeneration. DESIGN:Prospective, consecutive, interventional case series. PARTICIPANTS:Thirte...

journal_title：Ophthalmology

authors： Kadonosono K,Arakawa A,Yamane S,Inoue M,Yamakawa T,Uchio E,Yanagi Y

更新日期：2015-01-01 00:00:00

abstract：PURPOSE:To evaluate the efficacy of a single intravitreal injection of ocriplasmin 125 μg across relevant subpopulations of patients with symptomatic vitreomacular adhesion (VMA)/vitreomacular traction (VMT), including when associated with macular hole. DESIGN:Two multicenter, randomized, placebo-controlled, double-ma...

journal_title：Ophthalmology

authors： Haller JA,Stalmans P,Benz MS,Gandorfer A,Pakola SJ,Girach A,Kampik A,Jaffe GJ,Toth CA,MIVI-TRUST Study Group.

更新日期：2015-01-01 00:00:00

abstract：PURPOSE:To assess the development of vision-threatening lesions at least 3.5 years after initiating anti-vascular endothelial growth factor (VEGF) for choroidal neovascularization (CNV) in eyes with age-related macular degeneration (AMD). DESIGN:Retrospective cohort study. PARTICIPANTS:A total of 75 patients (81 eyes...

journal_title：Ophthalmology

authors： Tanaka E,Chaikitmongkol V,Bressler SB,Bressler NM

更新日期：2015-01-01 00:00:00

abstract：PURPOSE:This study aimed to identify the genetic defects in 2 families with autosomal recessive macular dystrophy with central cone involvement. DESIGN:Case series. PARTICIPANTS:Two families and a cohort of 244 individuals with various inherited maculopathies and cone disorders. METHODS:Genome-wide linkage analysis ...

journal_title：Ophthalmology

authors： Roosing S,van den Born LI,Sangermano R,Banfi S,Koenekoop RK,Zonneveld-Vrieling MN,Klaver CC,van Lith-Verhoeven JJ,Cremers FP,den Hollander AI,Hoyng CB

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:To compare pro re nata (PRN) and monthly injections of 0.5 mg ranibizumab in retinal vein occlusion (RVO) patients stabilized by monthly injections. DESIGN:Randomized, open-label, vision-examiner masked, 15-month study. PARTICIPANTS:Subjects with macular edema secondary to branch or central RVO. METHODS:Su...

journal_title：Ophthalmology

authors： Campochiaro PA,Wykoff CC,Singer M,Johnson R,Marcus D,Yau L,Sternberg G

更新日期：2014-12-01 00:00:00

abstract：OBJECTIVE:To report the long-term efficacy and safety of the interleukin-6 receptor antagonist tocilizumab for refractory uveitis-related macular edema (ME). DESIGN:Retrospective cohort study. PARTICIPANTS:Eyes with uveitis seen at a single tertiary referral center for which ME was the principal cause of reduced visu...

journal_title：Ophthalmology

authors： Mesquida M,Molins B,Llorenç V,Sainz de la Maza M,Adán A

更新日期：2014-12-01 00:00:00

abstract：PURPOSE:To investigate the relationship between macular ganglion cell-inner plexiform layer (mGCIPL) thickness and estimated macular retinal ganglion cell (RGC) counts in glaucoma. DESIGN:Observational cohort study. PARTICIPANTS:Cross-sectional study of 77 healthy, 154 glaucoma suspect, and 159 glaucomatous eyes from...

journal_title：Ophthalmology

authors： Zhang C,Tatham AJ,Weinreb RN,Zangwill LM,Yang Z,Zhang JZ,Medeiros FA

更新日期：2014-12-01 00:00:00

abstract：OBJECTIVE:To evaluate extraocular muscle surgery associated with plaque brachytherapy for choroidal melanoma. DESIGN:Single-center retrospective cohort study. PARTICIPANTS:Three hundred twenty-nine eyes of 329 consecutive patients with clinically diagnosed choroidal melanoma. INTERVENTION:Palladium 103 plaque brachy...

journal_title：Ophthalmology

authors： Nagendran ST,Finger PT,Campolattaro BN

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:We conducted a meta-analysis of randomized trials of ranibizumab for age-related macular degeneration (AMD) to elucidate systemic vascular risk. CLINICAL RELEVANCE:Although intravitreal vascular endothelial growth factor inhibitors are widely used to treat AMD, whether they produce systemic adverse effects ...

journal_title：Ophthalmology

authors： Ueta T,Noda Y,Toyama T,Yamaguchi T,Amano S

更新日期：2014-11-01 00:00:00

abstract：OBJECTIVE:To determine agreement between spectral-domain (SD) and time-domain (TD) optical coherence tomography (OCT) image assessments by certified readers in eyes treated for neovascular age-related macular degeneration (AMD). DESIGN:Cross-sectional study within the Comparison of AMD Treatments Trials (CATT). PARTI...

journal_title：Ophthalmology

authors： Folgar FA,Jaffe GJ,Ying GS,Maguire MG,Toth CA,Comparison of Age-Related Macular Degeneration Treatments Trials Research Group.

更新日期：2014-10-01 00:00:00

abstract：PURPOSE:To describe associations between reticular pseudodrusen, individual characteristics, and retinal function. DESIGN:Cohort study. PARTICIPANTS:We recruited 105 patients (age range, 52-93 years) who had advanced neovascular age-related macular degeneration (AMD) in only 1 eye from 3 clinical centers in Europe. ...

journal_title：Ophthalmology

authors： Hogg RE,Silva R,Staurenghi G,Murphy G,Santos AR,Rosina C,Chakravarthy U

更新日期：2014-09-01 00:00:00

abstract：PURPOSE:To determine the incidence and types of posterior staphylomas in eyes with pathologic myopia by analyzing the entire eye shape by 3-dimensional (3D) magnetic resonance imaging (MRI). DESIGN:Observational, case series. PARTICIPANTS:A total of 105 patients with pathologic myopia (spherical equivalent <-8.0 diop...

journal_title：Ophthalmology

authors： Ohno-Matsui K

更新日期：2014-09-01 00:00:00

abstract：OBJECTIVE:To identify risk factors associated with failure of anatomic reattachment in primary rhegmatogenous retinal detachment repair. DESIGN:Nonrandomized, multicenter, collaborative study. PARTICIPANTS:Primary procedures for 7678 rhegmatogenous retinal detachments reported by 176 surgeons from 48 countries. METH...

journal_title：Ophthalmology

authors： Adelman RA,Parnes AJ,Michalewska Z,Ducournau D,European Vitreo-Retinal Society (EVRS) Retinal Detachment Study Group.

更新日期：2014-09-01 00:00:00

abstract：PURPOSE:To investigate postoperative macular ganglion cell-inner plexiform layer (GCIPL) thickness, determine the factors related to GCIPL thickness, and evaluate the association of GCIPL thickness with postoperative visual outcomes in patients with idiopathic epiretinal membrane (ERM). DESIGN:Retrospective, cohort st...

journal_title：Ophthalmology

authors： Lee EK,Yu HG

更新日期：2014-08-01 00:00:00

abstract：OBJECTIVE:To evaluate the association between focal, structural defects of the lamina cribrosa (LC) and glaucomatous visual field (VF) progression. DESIGN:Retrospective, observational study. PARTICIPANTS:A total of 169 patients with glaucoma (169 eyes) with a range of glaucomatous damage. METHODS:Serial horizontal a...

journal_title：Ophthalmology

authors： Faridi OS,Park SC,Kabadi R,Su D,De Moraes CG,Liebmann JM,Ritch R

更新日期：2014-08-01 00:00:00

abstract：PURPOSE:To compare 3-year outcomes and complications of the Ahmed FP7 Glaucoma Valve (AGV) (New World Medical, Cucamonga, CA) and the Baerveldt Glaucoma Implant (BGI) 101-350 (Abbott Medical Optics, Abbott Park, IL) for the treatment of refractory glaucoma. DESIGN:Multicenter, randomized, controlled clinical trial. P...

journal_title：Ophthalmology

authors： Barton K,Feuer WJ,Budenz DL,Schiffman J,Costa VP,Godfrey DG,Buys YM,Ahmed Baerveldt Comparison Study Group.

更新日期：2014-08-01 00:00:00

abstract：PURPOSE:To assess quantitatively the depth of retinal nerve fiber layer (RNFL) defects using a Cirrus high-definition (HD) optical coherence tomography (OCT)-derived RNFL thickness deviation map. DESIGN:Prospective, cross-sectional study. PARTICIPANTS:Three-hundred fifteen eyes with localized and diffuse RNFL defects...

journal_title：Ophthalmology

authors： Suh MH,Yoo BW,Kim JY,Choi YJ,Park KH,Kim HC

更新日期：2014-07-01 00:00:00

abstract：OBJECTIVE:To demonstrate the corneal morphologic aspects obtained with in vivo confocal microscopy (CM) and light and electron microscopy of specimens obtained from the same patients with macular corneal dystrophy (MCD). DESIGN:Case series. PARTICIPANTS:Five consecutive patients affected by MCD undergoing penetrating...

journal_title：Ophthalmology

authors： Micali A,Pisani A,Puzzolo D,Nowińska A,Wylegala E,Teper S,Czajka E,Roszkowska AM,Orzechowska-Wylegala B,Aragona P

更新日期：2014-06-01 00:00:00

abstract：OBJECTIVE:To examine whether oral fluoroquinolone antibiotics are associated with an increase in subsequent rhegmatogenous retinal detachment and symptomatic retinal breaks in a large population-based cohort. DESIGN:Population-based cohort study. PARTICIPANTS AND CONTROLS:Adult residents of Olmsted County, Minnesota,...

journal_title：Ophthalmology

authors： Kapoor KG,Hodge DO,St Sauver JL,Barkmeier AJ

更新日期：2014-06-01 00:00:00

abstract：PURPOSE:To evaluate the outcomes of changing immunosuppressive therapy for noninfectious uveitis after failure. DESIGN:Retrospective cohort study. PARTICIPANTS:Patients with noninfectious uveitis managed at 2 tertiary uveitis clinics in the United Kingdom and Australia. METHODS:Participants with a history of using i...

journal_title：Ophthalmology

authors： Joshi L,Talat L,Yaganti S,Sandhu S,Taylor SR,Wakefield D,McCluskey P,Lightman S

更新日期：2014-05-01 00:00:00

abstract：PURPOSE:To evaluate the life and professional work of the English ophthalmologist Herbert Herbert (1865-1942). DESIGN:Historical study. METHODS:The main sources for this investigation are Herbert's approximately 65 published papers and 3 monographs. Other sources are contemporary publications by other ophthalmologist...

journal_title：Ophthalmology

authors： Feibel RM

更新日期：2014-05-01 00:00:00

abstract：PURPOSE:We sought to determine the most cost-effective treatment for patients with newly diagnosed neovascular macular degeneration: monthly or as-needed bevacizumab injections, or monthly or as-needed ranibizumab injections. DESIGN:Cost-effectiveness analysis. PARTICIPANTS:Hypothetical cohort of 80-year-old patients...

journal_title：Ophthalmology

authors： Stein JD,Newman-Casey PA,Mrinalini T,Lee PP,Hutton DW

更新日期：2014-04-01 00:00:00

abstract：PURPOSE:To evaluate and compare the structural differences of the ciliary body in eyes with and without malignant glaucoma. DESIGN:Cross-sectional study. PARTICIPANTS:Twenty-seven consecutive patients diagnosed with malignant glaucoma in 1 eye after trabeculectomy were recruited. They were all originally diagnosed wi...

journal_title：Ophthalmology

authors： Wang Z,Huang J,Lin J,Liang X,Cai X,Ge J

更新日期：2014-04-01 00:00:00

abstract：OBJECTIVE:To assess associations between health-related quality of life (HRQOL) and the decision to perform strabismus surgery for children with intermittent exotropia. DESIGN:Retrospective chart review. PARTICIPANTS:Children with intermittent exotropia. METHODS:Included subjects, identified in a clinical practice, ...

journal_title：Ophthalmology

authors： Hatt SR,Leske DA,Liebermann L,Mohney BG,Brodsky MC,Yamada T,Holmes JM

更新日期：2014-04-01 00:00:00

abstract：PURPOSE:To investigate the associations of genetic variants in the high-density lipoprotein (HDL) metabolism pathway with neovascular age-related macular degeneration (AMD) and polypoidal choroidal vasculopathy (PCV). DESIGN:Cross-sectional, case-control association study. PARTICIPANTS:A Chinese case-control group of...

journal_title：Ophthalmology

authors： Liu K,Chen LJ,Lai TY,Tam PO,Ho M,Chiang SW,Liu DT,Young AL,Yang Z,Pang CP

更新日期：2014-04-01 00:00:00

abstract：PURPOSE:To identify factors predictive of remission of inflammation in new-onset anterior uveitis cases treated at tertiary uveitis care facilities. DESIGN:Retrospective cohort study. PARTICIPANTS:Patients seeking treatment at participating academic uveitis clinics within 90 days of initial diagnosis of anterior uvei...

journal_title：Ophthalmology

authors： Artornsombudh P,Pistilli M,Foster CS,Pujari SS,Gangaputra SS,Jabs DA,Levy-Clarke GA,Nussenblatt RB,Rosenbaum JT,Suhler EB,Thorne JE,Kempen JH

更新日期：2014-03-01 00:00:00

abstract：PURPOSE:To report the histopathologic findings of a series of patients from an outbreak of Streptococcal endophthalmitis after intravitreal injection of bevacizumab prepared by a single compounding pharmacy. DESIGN:Case series. PARTICIPANTS:Seven surgical specimens (5 enucleated globes and 2 evisceration specimens) f...

journal_title：Ophthalmology

authors： Matthews JL,Dubovy SR,Goldberg RA,Flynn HW Jr

更新日期：2014-03-01 00:00:00

abstract：PURPOSE:To evaluate the effect of eculizumab, a systemic inhibitor of complement component (C5), on the growth of geographic atrophy (GA) in patients with age-related macular degeneration (AMD). DESIGN:Prospective, double-masked, randomized clinical trial. PARTICIPANTS:Patients with GA measuring from 1.25 to 18 mm(2)...

journal_title：Ophthalmology

authors： Yehoshua Z,de Amorim Garcia Filho CA,Nunes RP,Gregori G,Penha FM,Moshfeghi AA,Zhang K,Sadda S,Feuer W,Rosenfeld PJ

更新日期：2014-03-01 00:00:00

abstract：PURPOSE:To examine the hypotheses that in glaucomatous eyes with single-hemifield damage, retinal blood flow (RBF) is significantly reduced in the retinal hemisphere corresponding with the abnormal visual hemifield and that there are significant associations among reduced retinal sensitivity (RS) in the abnormal hemifi...

journal_title：Ophthalmology

authors： Sehi M,Goharian I,Konduru R,Tan O,Srinivas S,Sadda SR,Francis BA,Huang D,Greenfield DS

更新日期：2014-03-01 00:00:00

abstract：PURPOSE:To use in vivo confocal microscopy (IVCM) to quantitatively analyze microstructural changes over time, after corneal collagen cross-linking for keratoconus. DESIGN:Prospective cohort study. PARTICIPANTS:A total of 38 eyes of 38 patients undergoing collagen cross-linking for keratoconus. METHODS:Prospective, ...

journal_title：Ophthalmology

authors： Jordan C,Patel DV,Abeysekera N,McGhee CN

更新日期：2014-02-01 00:00:00